Overexpression of the TGFbeta-regulated zinc finger encoding gene, TIEG, induces apoptosis in pancreatic epithelial cells.

Members of the TGFbeta family of peptides exert antiproliferative effects and induce apoptosis in epithelial cell populations. In the exocrine pancreas, these peptides not only regulate normal cell growth, but alterations in these pathways have been associated with neoplastic transformation. Therefo...

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Autores principales: Tachibana, I, Imoto, M, Adjei, P N, Gores, G J, Subramaniam, M, Spelsberg, T C, Urrutia, R
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC508075/
https://ncbi.nlm.nih.gov/pubmed/9153278
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