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A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis.

The biological effects of the p53 tumor suppressor protein are elicited, at least in part, through sequence-specific transactivation of a battery of target genes. The differential display method was employed towards identifying additional p53 target genes, with emphasis on genes whose induction may...

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Detalhes bibliográficos
Main Authors: Israeli, D, Tessler, E, Haupt, Y, Elkeles, A, Wilder, S, Amson, R, Telerman, A, Oren, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170064/
https://ncbi.nlm.nih.gov/pubmed/9250682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.14.4384
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