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Downregulation of cyclin-dependent kinase 2 activity and cyclin A promoter activity in vascular smooth muscle cells by p27(KIP1), an inhibitor of neointima formation in the rat carotid artery.

Abnormal proliferation of vascular smooth muscle cells (VSMCs) contributes to intimal hyperplasia during atherosclerosis and restenosis, but the endogenous cell cycle regulatory factors underlying VSMC growth in response to arterial injury are not well understood. In the present study, we report tha...

詳細記述

保存先:
書誌詳細
出版年:J Clin Invest
主要な著者: Chen, D, Krasinski, K, Sylvester, A, Chen, J, Nisen, P D, Andrés, V
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508071/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9153274/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119414
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