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Genetics of immune-mediated disorders: from genome-wide association to molecular mechanism
Genetic association studies have identified not only hundreds of susceptibility loci to immune-mediated diseases but also pinpointed causal amino-acid variants of HLA genes that contribute to many autoimmune reactions. Majority of non-HLA genetic variants are located within non-coding regulatory reg...
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| 發表在: | Curr Opin Immunol |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5080657/ https://ncbi.nlm.nih.gov/pubmed/25458995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2014.09.007 |
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