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Genetics of immune-mediated disorders: from genome-wide association to molecular mechanism

Genetic association studies have identified not only hundreds of susceptibility loci to immune-mediated diseases but also pinpointed causal amino-acid variants of HLA genes that contribute to many autoimmune reactions. Majority of non-HLA genetic variants are located within non-coding regulatory reg...

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Podrobná bibliografie
Vydáno v:Curr Opin Immunol
Hlavní autoři: Kumar, Vinod, Wijmenga, Cisca, Xavier, Ramnik J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080657/
https://ncbi.nlm.nih.gov/pubmed/25458995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2014.09.007
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