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Angiotensin II type-1 receptor (AT(1)R) regulates expansion, differentiation, and functional capacity of antigen-specific CD8(+) T cells

Angiotensin II (Ang II) and its receptor AT(1) (AT(1)R), an important effector axis of renin-angiotensin system (RAS), have been demonstrated to regulate T-cell responses. However, these studies characterized Ang II and AT(1)R effects using pharmacological tools, which do not target only Ang II/AT(1...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Silva-Filho, João Luiz, Caruso-Neves, Celso, Pinheiro, Ana Acacia Sá
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080615/
https://ncbi.nlm.nih.gov/pubmed/27782175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35997
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