Sib-pair analysis detects elevated Lp(a) levels and large variation of Lp(a) concentration in subjects with familial defective ApoB.

Whether or not Lp(a) plasma levels are affected by the apoB R3500Q mutation, which causes Familial Defective apoB (FDB), is still a matter of debate. We have analyzed 300 family members of 13 unrelated Dutch index patients for the apoB mutation and the apolipoprotein(a) [apo(a)] genotype. Total chol...

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Detalhes bibliográficos
Main Authors: van der Hoek, Y. Y., Lingenhel, A., Kraft, H. G., Defesche, J. C., Kastelein, J. J., Utermann, G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508059/
https://ncbi.nlm.nih.gov/pubmed/9151801
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