ApoB-48 and apoB-100 differentially influence the expression of type-III hyperlipoproteinemia in APOE*2 mice

Apolipoprotein E (apoE) is essential for the clearance of plasma chylomicron and VLDL remnants. The human APOE locus is polymorphic and 5–10% of APOE*2 homozygotes exhibit type-III hyperlipoproteinemia (THL), while the remaining homozygotes have less than normal plasma cholesterol. In contrast, mice...

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Principais autores:	Myron E. Hinsdale, Patrick M. Sullivan, Hafid Mezdour, Nobuyo Maeda
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2002-09-01
叢編:	Journal of Lipid Research
主題:	lipoproteins very low density lipoprotein metabolism lipoprotein remnants
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S0022227520328169
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