TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis

Triggering receptor expressed on myeloid cells-1 (TREM-1) is a potent amplifier of pro-inflammatory innate immune responses, but its significance in non-infectious diseases remains unclear. Here, we demonstrate that TREM-1 promotes cardiovascular disease by exacerbating atherosclerosis. TREM-1 is ex...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Zysset, Daniel, Weber, Benjamin, Rihs, Silvia, Brasseit, Jennifer, Freigang, Stefan, Riether, Carsten, Banz, Yara, Cerwenka, Adelheid, Simillion, Cedric, Marques-Vidal, Pedro, Ochsenbein, Adrian F., Saurer, Leslie, Mueller, Christoph
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080444/
https://ncbi.nlm.nih.gov/pubmed/27762264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13151
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