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3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.

Oxidation of LDL may be of pivotal importance in atherogenesis, but the mechanisms that promote oxidation in vivo remain poorly understood. We have explored the possibility that one pathway involves myeloperoxidase, a heme protein secreted by phagocytes. Myeloperoxidase is the only human enzyme know...

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Sonraí Bibleagrafaíochta
Main Authors: Hazen, S. L., Heinecke, J. W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 1997
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC508036/
https://ncbi.nlm.nih.gov/pubmed/9151778
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