Prostaglandin E2 (PGE2) promotes proliferation and invasion by enhancing SUMO-1 activity via EP4 receptor in endometrial cancer

Prostaglandin E2 (PGE2), a derivative of arachidonic acid, has been identified as a tumorigenic factor in many cancers in recent studies. Prostaglandin E synthase 2 (PTGES2) is an enzyme that in humans is encoded by the PTGES2 gene located on chromosome 9, and it synthesizes PGE2 in human cells. In...

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Udgivet i:Tumour Biol
Main Authors: Ke, Jieqi, Yang, Yixia, Che, Qi, Jiang, Feizhou, Wang, Huihui, Chen, Zheng, Zhu, Minjiao, Tong, Huan, Zhang, Huilin, Yan, Xiaofang, Wang, Xiaojun, Wang, Fangyuan, Liu, Yuan, Dai, Chenyun, Wan, Xiaoping
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080328/
https://ncbi.nlm.nih.gov/pubmed/27230680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13277-016-5087-x
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