Antibody to VLA-4, but not to L-selectin, protects neuronal M2 muscarinic receptors in antigen-challenged guinea pig airways.

Antigen challenge of sensitized guinea pigs decreases the function of inhibitory M2 muscarinic autoreceptors on parasympathetic nerves in the lung, potentiating vagally induced bronchoconstriction. Loss of M2 receptor function is associated with the accumulation of eosinophils around airway nerves....

पूर्ण विवरण

ग्रंथसूची विवरण

में प्रकाशित:	J Clin Invest
मुख्य लेखकों:	Fryer, A D, Costello, R W, Yost, B L, Lobb, R R, Tedder, T F, Steeber, D A, Bochner, B S
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	American Society for Clinical Investigation 1997
विषय:	Research Article
ऑनलाइन पहुंच:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508029/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9109449/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119372
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