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A function for the QKRAA amino acid motif: mediating binding of DnaJ to DnaK. Implications for the association of rheumatoid arthritis with HLA-DR4.

The amino acid motif QKRAA, when expressed on HLA-DRB1, carries susceptibility to develop rheumatoid arthritis. This motif is the basis of strong B and T cell epitopes. Furthermore, it is highly overrepresented in protein databases, suggesting that it carries a function of its own. To identify this...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Auger, I, Roudier, J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC508005/
https://ncbi.nlm.nih.gov/pubmed/9109425
Etiketler: Etiketle
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