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(1S,2E,4S,7E,11E)-2,7,11-Cembratriene-4,6-diol Semisynthetic Analogs as Novel c-Met Inhibitors for The Control of c-Met-Dependent Breast Malignancies
(1S,2E,4S,6R,7E,11E)-2,7,11-cembratriene-4,6-diol (1) and its 4-epi-analog (2) are the cembranoid precursors to several key flavor ingredients in most Nicotiana (tobacco) species. Nearly 40–60% of 1 and 2 are purposely degraded during the commercial tobacco fermentation. However, 1 and 2 display pro...
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| Publicat a: | Bioorg Med Chem |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5079820/ https://ncbi.nlm.nih.gov/pubmed/27681240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.09.032 |
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