Neuroprotective Activity of (1S,2E,4R,6R,-7E,11E)-2,7,11-cembratriene-4,6-diol (4R) in vitro and in vivo in Rodent Models of Brain Ischemia

(1S,2E,4R,6R,-7E,11E)-2,7,11-cembratriene-4,6-diol (4R) is a precursor to key flavor ingredients in leaves of Nicotiana species. The present study shows 4R decreased brain damage in rodent ischemic stroke models. The 4R-pretreated mice had lower infarct volume (26.2±9.7 mm(3)) than those in control...

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Publicat a:Neuroscience
Autors principals: Martins, Antonio H, Hu, Jing, Xu, Zhenfeng, Mu, Chaofeng, Alvarez, Paloma, Ford, Byron D., El Sayed, Khalid, Eterovic, Vesna A., Ferchmin, Pedro A., Hao, Jiukuan
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369428/
https://ncbi.nlm.nih.gov/pubmed/25677097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2015.02.001
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