Dapagliflozin Enhances Fat Oxidation and Ketone Production in Patients With Type 2 Diabetes

OBJECTIVE: Insulin resistance is associated with mitochondrial dysfunction and decreased ATP synthesis. Treatment of individuals with type 2 diabetes mellitus (T2DM) with sodium–glucose transporter 2 inhibitors (SGLT2i) improves insulin sensitivity. However, recent reports have demonstrated developm...

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Vydáno v:Diabetes Care
Hlavní autoři: Daniele, Giuseppe, Xiong, Juan, Solis-Herrera, Carolina, Merovci, Aurora, Eldor, Roy, Tripathy, Devjit, DeFronzo, Ralph A., Norton, Luke, Abdul-Ghani, Muhammad
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2016
Témata:
Pathophysiology/Complications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079607/
https://ncbi.nlm.nih.gov/pubmed/27561923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc15-2688
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