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Correcting temperature-sensitive protein folding defects.

Recently, we found that different low molecular weight compounds, all known to stabilize proteins in their native conformation, are effective in correcting the temperature-sensitive protein folding defect associated with the deltaF508 cystic fibrosis transmembrane regulator (CFTR) protein. Here we e...

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Detalles Bibliográficos
Autores principales: Brown, C R, Hong-Brown, L Q, Welch, W J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC507959/
https://ncbi.nlm.nih.gov/pubmed/9077553
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