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Insulin-like growth factor receptor cooperates with integrin alpha v beta 5 to promote tumor cell dissemination in vivo.

Tumor cell interactions with adhesion proteins and growth factors likely contribute to the metastatic cascade. Evidence is provided that insulin or insulin-like growth factor-mediated signals cooperate with the commonly expressed integrin alpha v beta 5 to promote spontaneous pulmonary metastasis of...

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Detalles Bibliográficos
Main Authors: Brooks, P C, Klemke, R L, Schon, S, Lewis, J M, Schwartz, M A, Cheresh, D A
Formato: Artigo
Idioma:Inglês
Publicado: 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC507955/
https://ncbi.nlm.nih.gov/pubmed/9077549
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