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Ligand occupancy of the alpha-V-beta3 integrin is necessary for smooth muscle cells to migrate in response to insulin-like growth factor.

Smooth muscle cells (SMCs) have been shown to migrate in response to insulin-like growth factor I (IGF-I). However, the mechanism mediating this response has not been determined. The migration rates of porcine and human vascular SMCs were assessed in a monolayer wounding assay. IGF-I and IGF-II indu...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Jones, J I, Prevette, T, Gockerman, A, Clemmons, D R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39823/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8637900/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.6.2482
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