Plasma lipoprotein(a) levels and expression of the apolipoprotein(a) gene are dependent on the nucleotide polymorphisms in its 5'-flanking region.

The apolipoprotein(a) (apo[a]) gene encodes a protein component of lipoprotein(a) [Lp(a)] whose plasma levels vary widely among individuals. Hyper-Lp(a)-emia constitutes a risk factor for thromboembolic disease. We previously subclassified the apo(a) gene into four allelic types (A-D) by polymorphis...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Suzuki, K, Kuriyama, M, Saito, T, Ichinose, A
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507952/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9077546/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119295
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