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Common Single-Nucleotide Polymorphisms Act in Concert to Affect Plasma Levels of High-Density Lipoprotein Cholesterol

The identification of DNA sequence variants underlying human complex phenotypes remains a significant challenge for several reasons: individual variants can have small phenotypic effects or low population frequencies, and multiple allelic variants may act in concert to affect a trait. We evaluated t...

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Detalhes bibliográficos
Main Authors: Spirin, Victor , Schmidt, Steffen , Pertsemlidis, Alexander , Cooper, Richard S. , Cohen, Jonathan C. , Sunyaev, Shamil R. 
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Human Genetics 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276349/
https://ncbi.nlm.nih.gov/pubmed/17952847
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