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Mast cell tryptase stimulates the synthesis of type I collagen in human lung fibroblasts.

Mast cell activation is a characteristic feature of chronic inflammation, a condition that may lead to fibrosis as a result of increased collagen synthesis by fibroblasts. We have investigated the potential of tryptase, the major protease of human mast cells, to stimulate collagen synthesis in the h...

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Détails bibliographiques
Auteurs principaux: Cairns, J A, Walls, A F
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC507947/
https://ncbi.nlm.nih.gov/pubmed/9077541
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