Human mast cell tryptase stimulates the release of an IL-8-dependent neutrophil chemotactic activity from human umbilical vein endothelial cells (HUVEC)

Tryptase, the major product of human mast cell activation, is a potent stimulus of vascular leakage and neutrophil accumulation in vivo in animal studies, but the mechanisms of action remain unclear. Using HUVEC cultures we have sought to investigate the potential of tryptase to alter monolayer perm...

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Main Authors: Compton, S J, Cairns, J A, Holgate, S T, Walls, A F
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Science Inc 2000
Ábhair:
Allergy
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905680/
https://ncbi.nlm.nih.gov/pubmed/10886236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01271.x
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