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Cell cycle inhibition preserves endothelial function in genetically engineered rabbit vein grafts.

We have recently shown that ex vivo gene therapy of rabbit autologous vein grafts with antisense oligodeoxynucleotides (AS ODN) blocking cell cycle regulatory gene expression inhibits not only neointimal hyperplasia, but also diet-induced, accelerated graft atherosclerosis. We observed that these gr...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Mann, M J, Gibbons, G H, Tsao, P S, von der Leyen, H E, Cooke, J P, Buitrago, R, Kernoff, R, Dzau, V J
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1997
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507945/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9077539/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119288
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