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Cell cycle inhibition preserves endothelial function in genetically engineered rabbit vein grafts.

We have recently shown that ex vivo gene therapy of rabbit autologous vein grafts with antisense oligodeoxynucleotides (AS ODN) blocking cell cycle regulatory gene expression inhibits not only neointimal hyperplasia, but also diet-induced, accelerated graft atherosclerosis. We observed that these gr...

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Autors principals: Mann, M J, Gibbons, G H, Tsao, P S, von der Leyen, H E, Cooke, J P, Buitrago, R, Kernoff, R, Dzau, V J
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC507945/
https://ncbi.nlm.nih.gov/pubmed/9077539
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