Cell cycle inhibition preserves endothelial function in genetically engineered rabbit vein grafts.

We have recently shown that ex vivo gene therapy of rabbit autologous vein grafts with antisense oligodeoxynucleotides (AS ODN) blocking cell cycle regulatory gene expression inhibits not only neointimal hyperplasia, but also diet-induced, accelerated graft atherosclerosis. We observed that these gr...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Mann, M J, Gibbons, G H, Tsao, P S, von der Leyen, H E, Cooke, J P, Buitrago, R, Kernoff, R, Dzau, V J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507945/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9077539/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119288
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