Cell cycle inhibition preserves endothelial function in genetically engineered rabbit vein grafts.

We have recently shown that ex vivo gene therapy of rabbit autologous vein grafts with antisense oligodeoxynucleotides (AS ODN) blocking cell cycle regulatory gene expression inhibits not only neointimal hyperplasia, but also diet-induced, accelerated graft atherosclerosis. We observed that these gr...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Mann, M J, Gibbons, G H, Tsao, P S, von der Leyen, H E, Cooke, J P, Buitrago, R, Kernoff, R, Dzau, V J
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1997
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507945/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9077539/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119288
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