Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide.

Cartilage specimens from osteoarthritis (OA)-affected patients spontaneously released PGE2 at 48 h in ex vivo culture at levels at least 50-fold higher than in normal cartilage and 18-fold higher than in normal cartilage + cytokines + endotoxin. The superinduction of PGE2 production coincides with t...

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Autores principales: Amin, A R, Attur, M, Patel, R N, Thakker, G D, Marshall, P J, Rediske, J, Stuchin, S A, Patel, I R, Abramson, S B
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC507937/
https://ncbi.nlm.nih.gov/pubmed/9077531
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