Prolonged endothelin A receptor blockade attenuates chronic pulmonary hypertension in the ovine fetus.

Based on past studies of an experimental model of severe intrauterine pulmonary hypertension, we hypothesized that endothelin-1 (ET-1) contributes to high pulmonary vascular resistance (PVR), hypertensive lung structural changes, and right ventricular hypertrophy (RVH) caused by prolonged closure of...

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Detalhes bibliográficos
Main Authors: Ivy, D D, Parker, T A, Ziegler, J W, Galan, H L, Kinsella, J P, Tuder, R M, Abman, S H
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC507931/
https://ncbi.nlm.nih.gov/pubmed/9077525
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