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IL-15 functions as a danger signal to regulate tissue-resident T cells and tissue destruction

In this Opinion article, we discuss the function of tissues as a crucial checkpoint for the regulation of effector T cell responses, and the notion that interleukin-15 (IL-15) functions as a danger molecule that communicates to the immune system that the tissue is under attack and poises it to media...

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Detalhes bibliográficos
Publicado no:Nat Rev Immunol
Main Authors: Jabri, Bana, Abadie, Valérie
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079184/
https://ncbi.nlm.nih.gov/pubmed/26567920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3919
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