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The Role of Local Ancestry Adjustment in Association Studies Using Admixed Populations
1. For causal variants with similar effect size in all populations, power is generally higher in a study using admixed population than using nonadmixed population, especially for highly differentiated SNPs. This gain of power is achieved with adjustment of global ancestry, which completely removes a...
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| Udgivet i: | Genet Epidemiol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5079159/ https://ncbi.nlm.nih.gov/pubmed/25043967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21835 |
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