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Properties of Global and Local Ancestry Adjustments in Genetic Association Tests in Admixed Populations
Population substructure can lead to confounding in tests for genetic association, and failure to adjust properly can result in spurious findings. Here we address this issue of confounding by considering the impact of global ancestry (average ancestry across the genome) and local ancestry (ancestry a...
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| Publicado no: | Genet Epidemiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5811405/ https://ncbi.nlm.nih.gov/pubmed/29288582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22103 |
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