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Properties of Global and Local Ancestry Adjustments in Genetic Association Tests in Admixed Populations

Population substructure can lead to confounding in tests for genetic association, and failure to adjust properly can result in spurious findings. Here we address this issue of confounding by considering the impact of global ancestry (average ancestry across the genome) and local ancestry (ancestry a...

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Bibliografski detalji
Izdano u:Genet Epidemiol
Glavni autori: Martin, Eden R., Tunc, Ilker, Liu, Zhi, Slifer, Susan H., Beecham, Ashley H., Beecham, Gary W.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811405/
https://ncbi.nlm.nih.gov/pubmed/29288582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22103
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