BubR1 Insufficiency Results in Decreased Macrophage Proliferation and Attenuated Atherogenesis in Apolipoprotein E‐Deficient Mice

BACKGROUND: Budding uninhibited by benzimidazole‐related 1 (BubR1), a cell cycle–related protein, is an essential component of the spindle checkpoint that regulates cell division. BubR1 insufficiency causes early aging‐associated vascular phenotypes. We generated low‐BubR1‐expressing mutant (BubR1 (...

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Vydáno v:J Am Heart Assoc
Hlavní autoři: Tanaka, Shinichi, Matsumoto, Takuya, Matsubara, Yutaka, Harada, Yui, Kyuragi, Ryoichi, Koga, Jun‐ichiro, Egashira, Kensuke, Nakashima, Yutaka, Yonemitsu, Yoshikazu, Maehara, Yoshihiko
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079050/
https://ncbi.nlm.nih.gov/pubmed/27664806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.004081
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