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MKEY, a Peptide Inhibitor of CXCL4‐CCL5 Heterodimer Formation, Protects Against Stroke in Mice

BACKGROUND: MKEY, a synthetic cyclic peptide inhibitor of CXCL4–CCL5 heterodimer formation, has been shown to protect against atherosclerosis and aortic aneurysm formation by mediating inflammation, but whether it modulates neuroinflammation and brain injury has not been studied. We therefore studie...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Fan, Yifang, Xiong, Xiaoxing, Zhang, Yongming, Yan, Dongmei, Jian, Zhihong, Xu, Baohui, Zhao, Heng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079025/
https://ncbi.nlm.nih.gov/pubmed/27633389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003615
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