Systemic anaphylaxis in the mouse can be mediated largely through IgG1 and Fc gammaRIII. Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG1-dependent passive anaphylaxis.

We attempted to elicit active anaphylaxis to ovalbumin, or passive IgE- or IgG1-dependent anaphylaxis, in mice lacking either the Fc epsilonRI alpha chain or the FcR gamma chain common to Fc epsilonRI and Fc gammaRI/III, or in mice lacking mast cells (KitW/ KitW-v mice), and compared the responses t...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Miyajima, I, Dombrowicz, D, Martin, T R, Ravetch, J V, Kinet, J P, Galli, S J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507898/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9062348/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119255
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