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Extensive RNA editing and splicing increase immune self-representation diversity in medullary thymic epithelial cells
BACKGROUND: In order to become functionally competent but harmless mediators of the immune system, T cells undergo a strict educational program in the thymus, where they learn to discriminate between self and non-self. This educational program is, to a large extent, mediated by medullary thymic epit...
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| Gepubliceerd in: | Genome Biol |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5078920/ https://ncbi.nlm.nih.gov/pubmed/27776542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1079-9 |
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