Angiotensin-independent mechanism for aldosterone synthesis during chronic extracellular fluid volume depletion.

Wild-type (Agt+/+) and homozygous angiotensinogen deletion mutant (Agt-/-) littermates were placed on normal (NS) or low Na diet (LS) for 2 weeks. Plasma aldosterone levels (P(aldo)) were comparable during NS, and similarly elevated during LS in Agt+/+ and Agt-/-. Moreover, in both, the elevation in...

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Pubblicato in:	J Clin Invest
Autori principali:	Okubo, S, Niimura, F, Nishimura, H, Takemoto, F, Fogo, A, Matsusaka, T, Ichikawa, I
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507892/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9062342/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119249
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