Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia

Causes of the well-documented association between low levels of cognitive functioning and many adverse neuropsychiatric outcomes, poorer physical health and earlier death remain unknown. We used linkage disequilibrium regression and polygenic profile scoring to test for shared genetic aetiology betw...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Hagenaars, S P, Harris, S E, Davies, G, Hill, W D, Liewald, D C M, Ritchie, S J, Marioni, R E, Fawns-Ritchie, C, Cullen, B, Malik, R, Worrall, B B, Sudlow, C L M, Wardlaw, J M, Gallacher, J, Pell, J, McIntosh, A M, Smith, D J, Gale, C R, Deary, I J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078856/
https://ncbi.nlm.nih.gov/pubmed/26809841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.225
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