Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia

Causes of the well-documented association between low levels of cognitive functioning and many adverse neuropsychiatric outcomes, poorer physical health and earlier death remain unknown. We used linkage disequilibrium regression and polygenic profile scoring to test for shared genetic aetiology betw...

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Bibliografiske detaljer
Udgivet i:	Mol Psychiatry
Main Authors:	Hagenaars, S P, Harris, S E, Davies, G, Hill, W D, Liewald, D C M, Ritchie, S J, Marioni, R E, Fawns-Ritchie, C, Cullen, B, Malik, R, Worrall, B B, Sudlow, C L M, Wardlaw, J M, Gallacher, J, Pell, J, McIntosh, A M, Smith, D J, Gale, C R, Deary, I J
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2016
Fag:	Original Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5078856/ https://ncbi.nlm.nih.gov/pubmed/26809841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.225
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Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia

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