Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis

Although evidence for mitochondrial dysfunction in the pathogenesis of bipolar disorder (BD) has been reported, the precise biological basis remains unknown, hampering the search for novel biomarkers. In this study, we performed metabolomics of cerebrospinal fluid (CSF) from male BD patients (n=54)...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Mol Psychiatry
Hauptverfasser: Yoshimi, N, Futamura, T, Bergen, S E, Iwayama, Y, Ishima, T, Sellgren, C, Ekman, C J, Jakobsson, J, Pålsson, E, Kakumoto, K, Ohgi, Y, Yoshikawa, T, Landén, M, Hashimoto, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078854/
https://ncbi.nlm.nih.gov/pubmed/26782057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.217
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge