Role of MgADP in the development of diastolic dysfunction in the intact beating rat heart.

Sarcomere relaxation depends on dissociation of actin and myosin, which is regulated by a number of factors, including intracellular [MgATP] as well as MgATP hydrolysis products [MgADP] and inorganic phosphate [Pi], pHi, and cytosolic calcium concentration ([Ca2+]c). To distinguish the contribution...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Tian, R, Christe, M E, Spindler, M, Hopkins, J C, Halow, J M, Camacho, S A, Ingwall, J S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507859/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9045879/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119220
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