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Purification of a plasma membrane-associated GTPase-activating protein specific for rap1/Krev-1 from HL60 cells.

rap1/Krev-1 is a p21ras-related GTP-binding protein that has been implicated in the reversion of the ras-transformed cell phenotype. We have identified a GTPase-activating protein (GAP) specific for rap in plasma membranes isolated from differentiated HL60 cells. The rap GAP activity remained quanti...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Polakis, P G, Rubinfeld, B, Evans, T, McCormick, F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1991
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50785/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846040/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.1.239
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