The COOH-terminal domain of the Rap1A (Krev-1) protein is isoprenylated and supports transformation by an H-Ras:Rap1A chimeric protein.

Although the Rap1A protein resembles the oncogenic Ras proteins both structurally and biochemically, Rap1A exhibits no oncogenic properties. Rather, overexpression of Rap1A can reverse Ras-induced transformation of NIH 3T3 cells. Because the greatest divergence in amino acid sequence between Ras and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Buss, J E, Quilliam, L A, Kato, K, Casey, P J, Solski, P A, Wong, G, Clark, R, McCormick, F, Bokoch, G M, Der, C J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369437/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1899909/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.3.1523
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados