Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src

Despite the development of new antineoplastic agents for the treatment of colorectal cancer (CRC), oxaliplatin and fluoropyrimidines remain the most commonly employed drugs for the treatment of both early and advanced disease. Intrinsic or acquired resistance is, however, an important limitation to...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Perez, Marco, Lucena-Cacace, Antonio, Marín-Gómez, Luis Miguel, Padillo-Ruiz, Javier, Robles-Frias, Maria Jose, Saez, Carmen, Garcia-Carbonero, Rocio, Carnero, Amancio
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078079/
https://ncbi.nlm.nih.gov/pubmed/27105527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8880
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