Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis

Metabolic changes are associated with cancer, but whether they are just bystander effects of deregulated oncogenic signaling pathways or characterize early phases of tumorigenesis remains unclear. Here we show in a rat model of hepatocarcinogenesis that early preneoplastic foci and nodules that prog...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kowalik, Marta Anna, Guzzo, Giulia, Morandi, Andrea, Perra, Andrea, Menegon, Silvia, Masgras, Ionica, Trevisan, Elena, Angioni, Maria Maddalena, Fornari, Francesca, Quagliata, Luca, Ledda-Columbano, Giovanna Maria, Gramantieri, Laura, Terracciano, Luigi, Giordano, Silvia, Chiarugi, Paola, Rasola, Andrea, Columbano, Amedeo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078020/
https://ncbi.nlm.nih.gov/pubmed/27070090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8632
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