Gene silencing of indoleamine 2,3-dioxygenase 2 in melanoma cells induces apoptosis through the suppression of NAD+ and inhibits in vivo tumor growth

Indoleamine 2,3-dioxygenase 2 (IDO2) is a newly discovered enzyme that catalyzes the initial and rate-limiting step in the degradation of tryptophan. As a homologous protein of IDO1, IDO2 plays an inhibitory role in T cell proliferation, and it is essential for regulatory T cell (Treg) generation in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Yanling, Zhang, Yujuan, Zheng, Xiufen, Zhang, Xusheng, Wang, Hongmei, Li, Qin, Yuan, Keng, Zhou, Nanjing, Yu, Yanrong, Song, Na, Fu, Jiamin, Min, Weiping
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078016/
https://ncbi.nlm.nih.gov/pubmed/27058624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8617
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados