Transdominant inhibition of tyrosine kinase activity in mutant insulin/insulin-like growth factor I hybrid receptors.

Classical insulin and insulin-like growth factor I (IGF-I) receptors exist as well defined alpha 2 beta 2 heterotetrameric complexes that are assembled from two identical alpha beta heterodimeric half-receptor precursors. Recent evidence suggests that insulin and IGF-I half-receptors can heterologou...

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Detalhes bibliográficos
Main Authors: Treadway, J L, Morrison, B D, Soos, M A, Siddle, K, Olefsky, J, Ullrich, A, McClain, D A, Pessin, J E
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC50780/
https://ncbi.nlm.nih.gov/pubmed/1846039
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