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Changes in insulin-receptor structure associated with trypsin-induced activation of the receptor tyrosine kinase.

The tyrosine kinase of the insulin receptor can be activated by trypsin treatment. The concomitant abolition of insulin binding has been postulated to result from proteolytic destruction of the receptor. A discrepancy between the decrease in insulin binding and receptor immunoreactivity after trypsi...

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Detalhes bibliográficos
Main Authors: Clark, S, Eckardt, G, Siddle, K, Harrison, L C
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151138/
https://ncbi.nlm.nih.gov/pubmed/1645531
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