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Proteolytic generation of constitutive tyrosine kinase activity of the human insulin receptor.

Structural modification induced by partial digestion with trypsin has been shown to stimulate the tyrosine kinase activity of the insulin receptor both in solution and in intact cells [Tamura, Fujita-Yamaguchi & Larner (1983) J. Biol. Chem. 258, 14749-14752; Goren, White & Kahn (1987) Bioche...

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Main Authors: Hsuan, J J, Downward, J, Clark, S, Waterfield, M D
Formato: Artigo
Idioma:Inglês
Publicado: 1989
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138539/
https://ncbi.nlm.nih.gov/pubmed/2719663
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