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Sepsis is associated with increased mRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle.

Previous studies provided evidence that sepsis-induced muscle proteolysis in experimental animals is caused by increased ubiquitin-proteasome-dependent protein breakdown. It is not known if a similar mechanism accounts for muscle proteolysis in patients with sepsis. We determined mRNA levels for ubi...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Tiao, G, Hobler, S, Wang, J J, Meyer, T A, Luchette, F A, Fischer, J E, Hasselgren, P O
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507782/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9005983/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119143
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