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Energy-ubiquitin-dependent muscle proteolysis during sepsis in rats is regulated by glucocorticoids.

Recent studies suggest that sepsis-induced increase in muscle proteolysis mainly reflects energy-ubiquitin-dependent protein breakdown. We tested the hypothesis that glucocorticoids activate the energy-ubiquitin-dependent proteolytic pathway in skeletal muscle during sepsis. Rats underwent induction...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Tiao, G, Fagan, J, Roegner, V, Lieberman, M, Wang, J J, Fischer, J E, Hasselgren, P O
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1996
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507023/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8567953/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118421
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