Energy-ubiquitin-dependent muscle proteolysis during sepsis in rats is regulated by glucocorticoids.

Recent studies suggest that sepsis-induced increase in muscle proteolysis mainly reflects energy-ubiquitin-dependent protein breakdown. We tested the hypothesis that glucocorticoids activate the energy-ubiquitin-dependent proteolytic pathway in skeletal muscle during sepsis. Rats underwent induction...

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Pubblicato in:	J Clin Invest
Autori principali:	Tiao, G, Fagan, J, Roegner, V, Lieberman, M, Wang, J J, Fischer, J E, Hasselgren, P O
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507023/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8567953/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118421
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